⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329129 | 0.70 | — | — | |
| SCHEMBL22349236 | 0.68 | — | — | |
| Water SCHEMBL3793832 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL1996433 | 0.68 | — | — | |
| SCHEMBL12279963 | 0.68 | — | — | |
| SCHEMBL2869746 | 0.65 | HDAC8 (0.50) | — | |
| Acetic Acid SCHEMBL17238894 | 0.64 | HDAC8 (0.43) | — | |
| SCHEMBL486560 | 0.64 | HDAC8 (0.48) | — | |
| SCHEMBL21541646 | 0.64 | HDAC8 (0.48) | — | |
| SCHEMBL3002332 | 0.64 | HDAC8 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8398722-B2 | Phenylpyrido [1,2-A] indolium-derived thiol/disulfide dye, dye composition comprising this dye, process for lightening keratin materials using this dye | L'OREAL (FR) | 2013-03-19 | — | — | US | disclosed |
| US-20120266392-A1 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| US-8038732-B2 | Fluorescent entity, dyeing composition containing at least one fluorescent entity, and method for lightening keratin materials using said at least one fluorescent entity | L'OREAL S.A. (FR) | 2011-10-18 | — | — | US | disclosed |
| US-8034125-B2 | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | L'OREAL S.A. (FR) | 2011-10-11 | — | — | US | disclosed |
| US-20110016642-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL S.A. (FR) | 2011-01-27 | — | — | US | disclosed |
| US-20100287714-A1 | DYE COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT DYE COMPRISING AMINO GROUPS AND COMPRISING AN INTERNAL CATIONIC CHARGE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'ORÉAL (FR) | 2010-11-18 | — | — | US | disclosed |
| US-7744657-B2 | Styrl tetrahydroquinolinium thiol/disulfide dye compound and method for lightening keratin materials using the same | L'OREAL S.A. (FR) | 2010-06-29 | — | — | US | disclosed |
| US-7717964-B2 | Styryl thiol/disulfide compound with a hydroxy(cyclo)alkylamino unit, process for lightening keratin materials using same | L'OREAL S.A. (FR) | 2010-05-18 | — | — | US | disclosed |
| US-20090172897-A1 | STYRYL THIOL/DISULFIDE COMPOUND WITH A HYDROXY(CYCLO)ALKYLAMINO UNIT, PROCESS FOR LIGHTENING KERATIN MATERIALS USING SAME | L'OREAL S.A. (FR) | 2009-07-09 | — | — | US | disclosed |
| US-20090126125-A1 | STYRYL TETRAHYDROQUINOLINIUM THIOL/DISULFIDE DYE COMPOUND AND METHOD FOR LIGHTENING KERATIN MATERIALS USING THE SAME | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |