SCHEMBL12201705

SCHEMBL12201705

CCC(C)COc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
GAA P10253 2/20 0.55
PTGS2 P35354 1/20 0.54
MAPT P10636 4/20 0.52
BCL9 O00512 1/20 0.50
CTNNB1 P35222 1/20 0.50
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
FFAR1 O14842 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
BCHE P06276 1/20 0.46
ACHE P22303 1/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16479604 1.00 ALDH1A1 (0.56) ALDH1A1GAAPTGS2MAPTBCL9
SCHEMBL16479579 1.00 ALDH1A1 (0.56) ALDH1A1GAAPTGS2MAPTBCL9
SCHEMBL10643494 0.91 GAA (0.58) ALDH1A1GAAPTGS2MAPTCRHBP
SCHEMBL17795378 0.87 ALDH1A1 (0.57) ALDH1A1GAAPTGS2MAPTBCL9
SCHEMBL19683417 0.85 GAA (0.53) ALDH1A1GAAPTGS2MAPTCA1
SCHEMBL21157751 0.85 GAA (0.57) ALDH1A1GAAPTGS2MAPTCRHBP
SCHEMBL21157727 0.85 GAA (0.57) ALDH1A1GAAPTGS2MAPTCRHBP
SCHEMBL19683182 0.85 GAA (0.53) ALDH1A1GAAPTGS2MAPTCA1
SCHEMBL19201789 0.85 ALDH1A1 (0.57) ALDH1A1GAAPTGS2MAPTBCL9
SCHEMBL27183219 0.85 GAA (0.56) ALDH1A1GAAPTGS2MAPTBCL9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017129818-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES HUMBOLDT-UNIVERSITÄT ZU BERLIN (DE) 2017-08-03 WO disclosed
US-8034981-B2 Modified bio-related substance, process for producing the same, and intermediate NOF CORPORATION (JP) 2011-10-11 US disclosed
US-20110082277-A1 MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE NOF CORPORATION (JP) 2011-04-07 US disclosed