SCHEMBL12205490

SCHEMBL12205490

COc1ccc(-c2cc3c4c(c5c(c3cc2OC)OC(c2ccccc2)(c2ccc(N3CCOCC3)cc2)C=C5)C2(CC(C)(C)CC(C)(C)C2)c2ccccc2-4)c(OC)c1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
STK10 O94804 1/20 0.32
SLK Q9H2G2 1/20 0.32
ATR Q13535 1/20 0.31
ATRIP Q8WXE1 1/20 0.31
PIK3CA P42336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10021753 0.98 KDM4E (0.33) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL10262628 0.96 KDM4E (0.32) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL13868716 0.95 KDM4E (0.31) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL12189458 0.93 PRKDC (0.33) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL13868712 0.93 KDM4E (0.34) KDM4EALDH1A1MAPTHTTATR
SCHEMBL13868669 0.93 TTK (0.33) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL10292860 0.92 PRKDC (0.34) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL13868685 0.92 PRKDC (0.34) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL13868628 0.92 PRKDC (0.34) KDM4EALDH1A1MAPTHTTSTK10
SCHEMBL13868686 0.91 PRKDC (0.34) KDM4EALDH1A1MAPTSTK10SLK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2377902-A1 COATING COMPOSITION, PROCESS FOR PRODUCTION OF THE COMPOSITION, AND LAMINATE WITH HARD COAT LAYER Tokuyama Corporation (JP) 2011-10-19 EP disclosed
US-20110244244-A1 COATING COMPOSITION, PROCESS FOR PRODUCING THE COMPOSITION, AND LAMINATE HAVING A HARD COAT LAYER TOKUYAMA CORPORATION (JP) 2011-10-06 US disclosed