Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 20/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | SNCA | P37840 | 1/20 | 0.72 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464822 | 1.00 | APP (1.00) | APPMAPTSNCASULT1A1MEN1 | |
| SCHEMBL13806212 | 0.91 | APP (1.00) | APPMAPTSNCASULT1A1MEN1 | |
| SCHEMBL2628262 | 0.84 | APP (1.00) | APPMAPTSNCASULT1A1MEN1 | |
| Dimethylamine SCHEMBL27718704 | 0.84 | APP (0.72) | APPMAPTSNCASULT1A1MEN1 | |
| SCHEMBL178156 | 0.84 | APP (1.00) | APPMAPTSNCASULT1A1MEN1 | |
| SCHEMBL15425178 | 0.83 | APP (0.82) | APPMAPTSNCASULT1A1MEN1 | |
| SCHEMBL12207363 | 0.82 | SULT1A1 (0.75) | APPMAPTSULT1A1MEN1GAA | |
| Pittsburgh Compound B Unlabelled SCHEMBL912744 | 0.82 | APP (1.00) | APPMAPTSNCASULT1A1 | |
| SCHEMBL2466803 | 0.82 | APP (1.00) | APPMAPTSNCASULT1A1MEN1 | |
| SCHEMBL21043888 | 0.82 | APP (0.72) | APPMAPTSNCASULT1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110250136-A1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | SNU R&DB FOUNDATION (KR) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110250136-A1 | FLUORINATED BENZOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND IMAGING AGENT FOR DIAGNOSING ALTZHEIMER'S DISEASE USING THE SAME | APBA1, APP, PSEN1 | APP 2/4885MAPT 5/4885SNCA 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.