Shanzhiside Methyl Ester

Shanzhiside Methyl Ester

SCHEMBL12207355

COC(=O)C1=CO[C@@H](O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)C2C1[C@H](O)C[C@]2(C)O

nearest known ligand 0.62

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.62
▸ CTDSP1 Q9GZU7 1/20 0.62
▸ STAT3 P40763 15/20 0.59
▸ MAPT P10636 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ JUN P05412 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Shanzhiside Methyl Ester SCHEMBL29965826 1.00 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
Shanzhiside Methyl Ester SCHEMBL28007134 1.00 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
Shanzhiside SCHEMBL306203 0.90 MAPT (0.58) POLBCTDSP1STAT3MAPTMEN1
Barlerin SCHEMBL3244727 0.87 POLB (0.56) POLBCTDSP1STAT3MAPTMEN1
Barlerin SCHEMBL29425807 0.87 POLB (0.56) POLBCTDSP1STAT3MAPTMEN1
Lamalbid SCHEMBL9056954 0.85 POLB (0.66) POLBCTDSP1STAT3MAPTMEN1
SCHEMBL29425982 0.83 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
SCHEMBL9056451 0.83 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
Chlorotuberoside SCHEMBL29425799 0.83 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
Phlorigidoside C SCHEMBL29425891 0.82 POLB (0.61) POLBCTDSP1STAT3MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9433595-B2 Phytoestrogenic compositions for preventing or treating symptoms associated with menopause NATURAL ENDOTECH CO., LTD. (KR) 2016-09-06 — — US disclosed
US-9433595-B2 Phytoestrogenic compositions for preventing or treating symptoms associated with menopause NATURAL ENDOTECH CO., LTD. (KR) 2016-09-06 — — US disclosed
US-20110251145-A1 Phytoestrogenic Compositions for Preventing or Treating Symptoms Associated with Menopause NATURAL ENDOTECH CO., LTD. (KR) 2011-10-13 — — US disclosed
US-20110251145-A1 Phytoestrogenic Compositions for Preventing or Treating Symptoms Associated with Menopause NATURAL ENDOTECH CO., LTD. (KR) 2011-10-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251145-A1 Phytoestrogenic Compositions for Preventing or Treating Symptoms Associated with Menopause ESR1, CYP19A1, GPER1 POLB 4808/4885CTDSP1 4788/4885STAT3 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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