Barlerin

Barlerin

SCHEMBL3244727

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]2[C@@H]1[C@H](O)C[C@]2(C)OC(C)=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.56
▸ CTDSP1 Q9GZU7 1/20 0.56
▸ STAT3 P40763 15/20 0.56
▸ MAPT P10636 2/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barlerin SCHEMBL29425807 1.00 POLB (0.56) POLBCTDSP1STAT3MAPTMEN1
Shanzhiside Methyl Ester SCHEMBL12207355 0.87 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
Shanzhiside Methyl Ester SCHEMBL28007134 0.87 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
Shanzhiside Methyl Ester SCHEMBL29965826 0.87 POLB (0.62) POLBCTDSP1STAT3MAPTMEN1
SCHEMBL29425753 0.80 ELANE (0.58) POLBCTDSP1STAT3MAPTMEN1
SCHEMBL29425883 0.80 ELANE (0.58) POLBCTDSP1STAT3MAPTMEN1
Lamalbid SCHEMBL9056954 0.80 POLB (0.66) POLBCTDSP1STAT3MAPTMEN1
Phlorigidoside C SCHEMBL29425891 0.79 POLB (0.61) POLBCTDSP1STAT3MAPTMEN1
SCHEMBL3202619 0.78 HSP90AA1 (0.50) POLBCTDSP1STAT3MAPTMEN1
SCHEMBL29425776 0.78 POLB (0.52) POLBCTDSP1STAT3MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120078793-A Application of iridoid compound in parkinsonism neuroprotection drugs 桂林医学院附属医院 2025-06-03 — — CN claimed
WO-2024190919-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND ACID DIFFUSION CONTROL AGENT 東京応化工業株式会社 2024-09-19 — — WO claimed
CN-118272268-A Heterotrophic nitrification-aerobic denitrification paracymenia and application thereof 闽江学院 2024-07-02 — — CN claimed
CN-115657324-A Light combining mechanism and optical lens 广东科视光学技术股份有限公司 2023-01-31 — — CN claimed
EP-1496920-B1 PHARMACEUTICAL COMPOSITION CONTAINING AN EXTRACT FROM BARLERIA PRIONITIS LINN AND ITS PROCESS OF PREPARATION COUNCIL SCIENT IND RES (IN) 2010-03-03 — — EP claimed
EP-1496920-A1 PHARMACEUTICAL COMPOSITION CONTAINING AN EXTRACT FROM BARLERIA PRIONITIS LINN AND ITS PROCESS OF PREPARATION Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2005-01-19 — — EP claimed
US-6664236-B2 Mixtures of glucosides obtained by solvent extraction from plants, comprising barlerin, acetyl barlerin, shanshizide methyl esters and adjuvants, used for detoxification, immunomodulation and as anxiolytic agents COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-12-16 — — US claimed
WO-2003080087-A1 PHARMACEUTICAL COMPOSITION CONTAINING AN EXTRACT FROM BARLERIA PRIONITIS LINN AND ITS PROCESS OF PREPARATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 — — WO claimed
US-20030181397-A1 SYNERGISTIC COMPOSITION OF BIOACTIVE FRACTION ISOLATED BARLERIA PRIONITIS LINN AND A METHOD OF TREATMENT FOR HEPATOTOXICITY, IMMUNO-DEFICIENCY AND FATIGUE AND A PROCESS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2003-09-25 — — US claimed
CN-122075799-A Hydrogel for cartilage repair and preparation method thereof — 2026-05-26 — — CN disclosed
CN-122063760-A Ultra-wide-angle small-sized automatic focusing lens and image pickup device 深圳市唯卓仕科技有限公司 2026-05-19 — — CN disclosed
US-12580569-B2 Multi-bit level shifter TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-03-17 — — US disclosed
CN-121606591-A Breast cancer cell inhibitor containing 8-O-acetyl shanzhiside methyl ester and application thereof 桂林医科大学第一附属医院 2026-03-06 — — CN disclosed
US-12562720-B2 Method of forming semiconductor device including daisy-chained delay cells TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-02-24 — — US disclosed
CN-1627954-A Pharmaceutical compsn. contg. extract from barleria prionitis linn and its process of prepn COUNCIL SCIENT IND RES (IN) 2005-06-15 — — CN disclosed
EP-1496920-A1 PHARMACEUTICAL COMPOSITION CONTAINING AN EXTRACT FROM BARLERIA PRIONITIS LINN AND ITS PROCESS OF PREPARATION Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2005-01-19 — — EP disclosed
US-6664236-B2 Mixtures of glucosides obtained by solvent extraction from plants, comprising barlerin, acetyl barlerin, shanshizide methyl esters and adjuvants, used for detoxification, immunomodulation and as anxiolytic agents COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-12-16 — — US disclosed
WO-2003080087-A1 PHARMACEUTICAL COMPOSITION CONTAINING AN EXTRACT FROM BARLERIA PRIONITIS LINN AND ITS PROCESS OF PREPARATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 — — WO disclosed
US-20030181397-A1 SYNERGISTIC COMPOSITION OF BIOACTIVE FRACTION ISOLATED BARLERIA PRIONITIS LINN AND A METHOD OF TREATMENT FOR HEPATOTOXICITY, IMMUNO-DEFICIENCY AND FATIGUE AND A PROCESS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2003-09-25 — — US disclosed
WO-1996010408-A1 CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) 1996-04-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12580569-B2 Multi-bit level shifter HCN4, SOS2, CACNB2 POLB 4698/4885CTDSP1 4188/4885STAT3 252/4885
US-12562720-B2 Method of forming semiconductor device including daisy-chained delay cells DSP, DSC1, DSG1 POLB 2197/4885CTDSP1 231/4885STAT3 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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