Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373713 | 0.92 | MAPK1 (0.35) | MAPK1ADORA3KMT2APDE4DPIK3CA | |
| SCHEMBL30785591 | 0.70 | PDE4B (0.31) | PDE4DPDE4B | |
| SCHEMBL558118 | 0.69 | IL1B (0.35) | — | |
| SCHEMBL373536 | 0.69 | PDE4D (0.37) | KMT2APDE4D | |
| SCHEMBL195356 | 0.69 | MAPK1 (0.37) | MAPK1ADORA3KMT2APDE4DPIK3CA | |
| SCHEMBL31571877 | 0.68 | PDE4B (0.38) | PDE4DPDE4B | |
| SCHEMBL20851935 | 0.67 | MAPK1 (0.35) | MAPK1ADORA3KMT2APDE4DPIK3CA | |
| SCHEMBL20840622 | 0.67 | MAPK1 (0.35) | MAPK1ADORA3KMT2APDE4DPIK3CA | |
| SCHEMBL516176 | 0.67 | MAPK1 (0.35) | MAPK1ADORA3KMT2APDE4DPIK3CA | |
| SCHEMBL30678850 | 0.67 | PDE4B (0.34) | PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380891-A1 | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |