⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15905673 | 0.94 | — | — | |
| SCHEMBL19879375 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL15984383 | 0.72 | TDP1 (0.40) | — | |
| SCHEMBL15031021 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL15905907 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL12957762 | 0.70 | TSHR (0.42) | — | |
| SCHEMBL19731163 | 0.65 | — | — | |
| SCHEMBL12958786 | 0.65 | TSHR (0.48) | — | |
| SCHEMBL20310558 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL15984381 | 0.62 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452144-B2 | Method of using fibrous tissue sealant | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2016-09-27 | — | — | US | disclosed |
| US-20150196496-A1 | METHOD OF USING FIBROUS TISSUE SEALANT | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2015-07-16 | — | — | US | disclosed |
| US-9017703-B2 | Method of using fibrous tissue sealant | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-8545871-B2 | Fibrous tissue sealant and method of using same | ACTAMAX SURGICAL MATERIALS LLC (US) | 2013-10-01 | — | — | US | disclosed |
| US-8466327-B2 | Aldehyde-functionalized polyethers and method of making same | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110250257-A1 | FIBROUS TISSUE SEALANT AND METHOD OF USING SAME | ACTAMAX SURGICAL MATERIALS LLC | 2011-10-13 | — | — | US | disclosed |
| US-20100125155-A1 | ALDEHYDE-FUNCTIONALIZED POLYETHERS AND METHOD OF MAKING SAME | E.I. DU PONT NEMOURS AND COMPANY (US) | 2010-05-20 | — | — | US | disclosed |