SCHEMBL12215319

SCHEMBL12215319

C=C(C)C(=O)OCCc1cc(-n2n3c4ccc(OCC)cc4n23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ THRB P10828 2/20 0.32
▸ GAA P10253 5/20 0.32
▸ PKM P14618 1/20 0.32
▸ THRA P10827 1/20 0.31
▸ SRC P12931 1/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ EPHX2 P34913 1/20 0.30
▸ NR1H4 Q96RI1 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13400582 0.86 GAA (0.36) HTTGAAKMT2AALDH1A1MEN1
SCHEMBL12215317 0.86 GAA (0.32) GAAKMT2AALDH1A1MEN1LMNA
SCHEMBL12238614 0.84 GAA (0.30) GAA
SCHEMBL13159301 0.83 ALOX5 (0.34) HTTPOLBAPEX1TDP1GAA
SCHEMBL812980 0.83 ALOX5 (0.34) HTTPOLBAPEX1TDP1GAA
SCHEMBL13343253 0.81 SMN1; SMN2 (0.33) POLBALDH1A1
SCHEMBL12215322 0.81 GAA (0.37) HTTPOLBAPEX1TDP1GAA
SCHEMBL13159315 0.78 GAA (0.35) HTTPOLBAPEX1TDP1GAA
SCHEMBL812966 0.78 GAA (0.35) HTTPOLBAPEX1TDP1GAA
SCHEMBL813245 0.77 GAA (0.35) HTTTDP1GAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8039065-B2 Antireflection film, polarizing plate, method for producing them, liquid crystal display element, liquid crystal display device, and image display device FUJIFILM CORPORATION (JP) 2011-10-18 — — US disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 — — US disclosed
US-7815823-B2 Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2010-10-19 — — US disclosed
US-20100103352-A1 OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20100103352-A1 OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
US-20090316084-A1 Method of Producing Polarizing Plate, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-12-24 — — US disclosed
US-7622194-B2 use of a transparent support having specific physical properties during the spreading of a functional layer makes it possible to control the spread and the penetration of solvent and hence provide a good quality optical film having little coating defects, reducing impact of residual solvent; LCDs FUJIFILM CORPORATION (JP) 2009-11-24 — — US disclosed
US-20090286098-A1 Optical Film, Method of Producing the Same and Image Displaying Apparatus Employing the Optical Film KONICA MINOLTA OPTO, INC. (JP) 2009-11-19 — — US disclosed
US-20090135345-A1 Polarizing Plate Protective Film, Film Producing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-05-28 — — US disclosed
US-20070146887-A1 Antireflection film, polarizing plate, method for producing them, liquid cryatal display element, liquid crystal display device, and image display device FUJI PHOTO FILM CO., LTD. (JP) 2007-06-28 — — US disclosed
US-20070146887-A1 Antireflection film, polarizing plate, method for producing them, liquid cryatal display element, liquid crystal display device, and image display device FUJI PHOTO FILM CO., LTD. (JP) 2007-06-28 — — US disclosed
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