Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 1.00 |
| ▸ | DRD1 | P21728 | 3/20 | 1.00 |
| ▸ | DRD3 | P35462 | 3/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 1.00 |
| ▸ | IGF1R | P08069 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopexamine SCHEMBL29711811 | 1.00 | ADRB2 (1.00) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| SCHEMBL7278498 | 1.00 | ADRB2 (1.00) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| SCHEMBL7272201 | 1.00 | ADRB2 (1.00) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Dopexamine SCHEMBL5605569 | 1.00 | ADRB2 (1.00) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Bromide SCHEMBL7280381 | 0.98 | ADRB2 (0.97) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Dopexamine SCHEMBL29390436 | 0.98 | ADRB2 (0.97) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Dopexamine SCHEMBL5464371 | 0.98 | ADRB2 (0.97) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Dopexamine SCHEMBL123115 | 0.98 | ADRB2 (0.97) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Dopexamine SCHEMBL123114 | 0.98 | ADRB2 (0.97) | ADRB2DRD1DRD3ADORA3CHRM1 | |
| Bromide SCHEMBL7278354 | 0.98 | ADRB2 (0.97) | ADRB2DRD1DRD3ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3162 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213647-A1 | CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE | UNIVERSITY OF SOUTH FLORIDA | 2025-07-03 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| WO-2025092300-A1 | USE OF ADRENORECEPTOR AGONISTS IN PROMOTING HEMATOPOIETIC REGENERATION | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2025-05-08 | — | — | WO | claimed |
| CN-119233997-A | Tetrahedral antibodies | 生物分子控股有限责任公司 | 2024-12-31 | — | — | CN | claimed |
| US-20240398729-A1 | Methods and Compositions for the Treatment of Cytoplasmic Glycogen Storage Disorders | DUKE UNIVERSITY (US) | 2024-12-05 | — | — | US | claimed |
| EP-4463485-A2 | TETRAHEDRAL ANTIBODIES | Biomolecular Holdings LLC (US) | 2024-11-20 | — | — | EP | claimed |
| US-20240366586-A1 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | US | claimed |
| CN-118384290-A | Hybrid immunoglobulins containing non-peptide linkages | 生物分子控股有限责任公司 | 2024-07-26 | — | — | CN | claimed |
| CN-117462481-A | Promoter for promoting nasal delivery of pharmaceutical ingredients and application thereof | 南京星叶生物科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| US-20240025904-A1 | PDE9 INHIBITORS FOR TREATING CARDIAC FAILURE | VANDERBILT UNIVERSITY | 2024-01-25 | — | — | US | claimed |
| WO-2000054773-A1 | DOPAMINE AGONISTS IN COMBINATION WITH NITRIC OXIDE DONORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2000-09-21 | — | — | WO | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-0954327-A1 | USEFUL FORMULATIONS OF ACID ADDITION SALT DRUGS | OXIGENE, INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1998000159-A1 | USEFUL FORMULATIONS OF ACID ADDITION SALT DRUGS | OXIGENE, INC. (US) | 1998-01-08 | — | — | WO | claimed |
| US-5013760-A | Phenylethylamine derivatives and pharmaceutical use | FISONS PLC (GB) | 1991-05-07 | — | — | US | claimed |
| EP-0167204-B1 | METHOD FOR IMPROVING THE ABSORPTION AND EFFECTIVENESS OF A CATECHOLAMINE COMPOUND | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1989-09-27 | — | — | EP | claimed |
| EP-0117033-B1 | PHARMACEUTICAL FORMULATIONS | FISONS plc (GB) | 1987-09-30 | — | — | EP | claimed |
| US-4645768-A | TREATMENT OF CARDIOVASCULAR DISORDERS | FISONS PLC (GB) | 1987-02-24 | — | — | US | claimed |
| EP-0117033-A2 | Pharmaceutical formulations | FISONS plc (GB) | 1984-08-29 | — | — | EP | claimed |
| EP-0072061-A1 | Amine derivatives, processes for their production and pharmaceutical compositions containing them | FISONS plc (GB) | 1983-02-16 | — | — | EP | claimed |