⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30536993 | 0.72 | — | — | |
| SCHEMBL5853553 | 0.72 | — | — | |
| SCHEMBL30788722 | 0.72 | — | — | |
| SCHEMBL175558 | 0.72 | — | — | |
| SCHEMBL237 | 0.72 | — | — | |
| SCHEMBL28332730 | 0.72 | — | — | |
| Tetrachloroethylene SCHEMBL1555228 | 0.71 | TSHR (0.56) | — | |
| Tetrachloroethylene SCHEMBL20483364 | 0.67 | LMNA (0.60) | — | |
| Hydrochloric Acid SCHEMBL23420518 | 0.67 | — | — | |
| Hydrogen Sulfide SCHEMBL21359612 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867230-B1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLES | MONSANTO TECHNOLOGY LLC (US) | 2020-02-12 | — | — | EP | disclosed |
| WO-2017083867-A1 | ION CHANNEL INHIBITORY COMPOUNDS, PHARMACEUTICAL FORMULATIONS AND USES | AFASCI, INC. (US) | 2017-05-18 | — | — | WO | disclosed |
| US-9169233-B2 | Methods for the preparation of aryl amides | SYNGENTA LIMITED (GB) | 2015-10-27 | — | — | US | disclosed |
| US-9169233-B2 | Methods for the preparation of aryl amides | SYNGENTA LIMITED (GB) | 2015-10-27 | — | — | US | disclosed |
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| EP-2373625-B1 | METHODS FOR THE PREPARATION OF ARYL AMIDES | SYNGENTA LTD (GB) | 2014-10-08 | — | — | EP | disclosed |
| US-20140107348-A1 | METHODS FOR THE PREPARATION OF ARYL AMIDES | SYNGENTA LIMITED (GB) | 2014-04-17 | — | — | US | disclosed |
| US-20140107348-A1 | METHODS FOR THE PREPARATION OF ARYL AMIDES | SYNGENTA LIMITED (GB) | 2014-04-17 | — | — | US | disclosed |
| US-8637678-B2 | Methods for the preparation of aryl amides | SYNGENTA LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| US-8637678-B2 | Methods for the preparation of aryl amides | SYNGENTA LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| EP-2223910-B1 | OXIME ESTERS AND PHOTOPOLYMERIZATION INITIATORS CONTAINING THE SAME | ADEKA CORP (JP) | 2012-11-07 | — | — | EP | disclosed |
| EP-1143977-B3 | 2-OXY-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY | NORGINE BV (NL) | 2012-10-24 | — | — | EP | disclosed |
| US-20110263869-A1 | METHODS FOR THE PREPARATION OF ARYL AMIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263869-A1 | METHODS FOR THE PREPARATION OF ARYL AMIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |