⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122551 | 0.98 | — | — | |
| SCHEMBL1052042 | 0.92 | KDM1A (0.31) | — | |
| SCHEMBL1052040 | 0.92 | KDM1A (0.31) | — | |
| SCHEMBL6015270 | 0.92 | KDM1A (0.31) | — | |
| SCHEMBL3982960 | 0.92 | MAPT (0.31) | — | |
| SCHEMBL481597 | 0.90 | MAPT (0.30) | — | |
| SCHEMBL1049799 | 0.90 | MAPT (0.30) | — | |
| SCHEMBL7638599 | 0.88 | — | — | |
| SCHEMBL7637193 | 0.88 | — | — | |
| SCHEMBL7637190 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412393-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING CHELATING DIANIONIC LIGANDS | Equistar Chemicals, LP (US) | 2004-04-28 | — | — | EP | claimed |
| US-6544918-B1 | Efficiency | EQUISTAR CHEMICALS, LP | 2003-04-08 | — | — | US | claimed |
| US-20030055276-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING CHELATING DIANIONIC LIGANDS | EQUISTAR CHEMICALS, LP | 2003-03-20 | — | — | US | claimed |
| WO-2003008464-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING CHELATING DIANIONIC LIGANDS | EQUISTAR CHEMICALS, LP (US) | 2003-01-30 | — | — | WO | claimed |
| US-10117878-B2 | Ligands for nematode nuclear receptors and uses thereof | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2018-11-06 | — | — | US | disclosed |
| US-9856219-B2 | Substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors | NIVALIS THERAPEUTICS, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| EP-3247715-A1 | METHODS OF PREVENTING, REDUCING OR TREATING MACULAR DEGENERATION | Inotek Pharmaceuticals Corporation (US) | 2017-11-29 | — | — | EP | disclosed |
| US-9814700-B2 | Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents | NIVALIS THERAPEUTICS, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9707212-B2 | S-nitrosoglutathione reductase inhibitors | NIVALIS THERAPEUTICS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20170049750-A1 | Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents | LAUREL THERAPEUTICS LTD. (CN) | 2017-02-23 | — | — | US | disclosed |
| US-20160367586-A1 | COMBINATION, KIT AND METHOD OF REDUCING INTRAOCULAR PRESSURE | INOTEK PHARMACEUTICALS CORPORATION | 2016-12-22 | — | — | US | disclosed |
| EP-2555775-B1 | COMBINATION COMPOSITIONS OF ADENOSINE A1 AGONISTS AND CARBONIC ANHYDRASE INHIBITORS FOR REDUCING INTRAOCULAR PRESSURE | INOTEK PHARMACEUTICALS CORP (US) | 2016-12-07 | — | — | EP | disclosed |
| WO-2005118538-A2 | ARYLSULFONAMIDES AND USES AS HYDROXYSTEROID DEHYDROGENASE | AMGEN, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005110980-A2 | ARYL SULFONES AND USES RELATED THERETO | AMGEN, INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005063247-A1 | ARYL SULFONAMIDE COMPOUNDS AND USES RELATED THERETO | AMGEN INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005051942-A1 | INDAZOLE COMPOUNDS AND METHODS OF USE THEREOF AS PROTEIN KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2005-06-09 | — | — | WO | disclosed |
| EP-1412393-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING CHELATING DIANIONIC LIGANDS | Equistar Chemicals, LP (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6544918-B1 | Efficiency | EQUISTAR CHEMICALS, LP | 2003-04-08 | — | — | US | disclosed |
| US-20030055276-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING CHELATING DIANIONIC LIGANDS | EQUISTAR CHEMICALS, LP | 2003-03-20 | — | — | US | disclosed |
| WO-2003008464-A1 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING CHELATING DIANIONIC LIGANDS | EQUISTAR CHEMICALS, LP (US) | 2003-01-30 | — | — | WO | disclosed |