Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | KLK1 | P06870 | 3/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12242560 | 1.00 | THRB (0.39) | THRBKMT2AMAPTPRSS1KLK1 | |
| SCHEMBL12242484 | 0.88 | FFAR1 (0.41) | THRBKMT2AACACBTSHRMEN1 | |
| SCHEMBL12242527 | 0.88 | FFAR1 (0.41) | THRBKMT2AACACBTSHRMEN1 | |
| SCHEMBL12242519 | 0.86 | MAOB (0.34) | THRBPRSS1KLK1TMPRSS2ACACB | |
| SCHEMBL12242628 | 0.85 | THRB (0.50) | THRBKMT2AMAPTPRSS1KLK1 | |
| SCHEMBL12242529 | 0.84 | THRB (0.42) | THRBKMT2AMAPTACACB | |
| SCHEMBL12242528 | 0.84 | CA12 (0.43) | THRBKMT2AMAPTACACBMEN1 | |
| SCHEMBL12242530 | 0.84 | CA12 (0.43) | THRBKMT2AMAPTACACBMEN1 | |
| SCHEMBL12242502 | 0.84 | FFAR1 (0.39) | THRBACACBTSHRALDH1A1GAA | |
| SCHEMBL12242516 | 0.84 | KMT2A (0.36) | THRBKMT2AMAPTPRSS1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8460576-B2 | Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same | DIC CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20110253936-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |