Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191970 | 0.83 | CCNT1 (0.75) | CCNT1 | |
| SCHEMBL1192141 | 0.82 | CCNT1 (0.69) | CCNT1 | |
| SCHEMBL1225590 | 0.82 | CCNT1 (0.72) | CCNT1 | |
| SCHEMBL1192199 | 0.82 | CCNT1 (0.72) | CCNT1 | |
| SCHEMBL1192378 | 0.79 | CCNT1 (0.69) | CCNT1 | |
| SCHEMBL1192494 | 0.79 | CCNT1 (0.50) | CCNT1 | |
| SCHEMBL1462780 | 0.77 | CDK9 (0.47) | CCNT1 | |
| SCHEMBL9237011 | 0.77 | CCNT1 (0.54) | CCNT1 | |
| SCHEMBL1192498 | 0.76 | CCNT1 (0.51) | CCNT1 | |
| SCHEMBL9237007 | 0.75 | CCNT1 (0.57) | CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459535-A1 | PYRIDINE AND PYRAZINE DERIVATIVES AS PROTEIN KINASE MODULATORS | Novartis AG (CH) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012661-A1 | PYRIDINE AND PYRAZINE DERIVATIVES AS PROTEIN KINASE MODULATORS | NOVARTIS AG (CH) | 2011-02-03 | — | — | WO | disclosed |