Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12382100 | 0.89 | MEN1 (0.34) | MEN1KMT2AMAPTABCB11LMNA | |
| SCHEMBL20021197 | 0.86 | P2RX7 (0.33) | MEN1KMT2AMAPTABCB11P2RX7 | |
| SCHEMBL21082998 | 0.81 | HPGD (0.34) | MAPTP2RX7ALDH1A1SHMT1SHMT2 | |
| SCHEMBL21128298 | 0.80 | MAPT (0.34) | MAPTLMNAP2RX7ALDH1A1SHMT1 | |
| SCHEMBL22954436 | 0.80 | MAPT (0.32) | KMT2AMAPTLMNAP2RX7ALDH1A1 | |
| SCHEMBL21082986 | 0.79 | HPGD (0.33) | MAPTP2RX7ALDH1A1TSHR | |
| SCHEMBL21128193 | 0.79 | HPGD (0.33) | MAPTP2RX7ALDH1A1TSHR | |
| SCHEMBL21082993 | 0.78 | MAPT (0.32) | MAPTLMNAP2RX7ALDH1A1SHMT1 | |
| SCHEMBL12738955 | 0.78 | ANO1 (0.37) | MAPTLMNAP2RX7ALDH1A1SHMT1 | |
| SCHEMBL1153521 | 0.77 | LPAR1 (0.36) | MEN1KMT2AMAPTPLAUPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-8859466-B2 | Oxaspirocyclic spiro-substituted tetramic acid and tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20110263424-A1 | Oxaspirocyclic Spiro-Substituted Tetramic Acid and Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-10-27 | — | — | US | disclosed |
| WO-2009015801-A1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-02-05 | — | — | WO | disclosed |
| EP-2020413-A1 | Oxaspirocyclical spiro-substituted tetram and tetron acid derivatives | Bayer CropScience AG (DE) | 2009-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263424-A1 | Oxaspirocyclic Spiro-Substituted Tetramic Acid and Tetronic Acid Derivatives | TBCA, POF1B, DDT | MEN1 3983/4885KMT2A 4063/4885MAPT 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.