Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12263138 | 0.93 | CA12 (0.44) | MAPTLMNAPOLBCCR1ALDH1A1 | |
| SCHEMBL2398149 | 0.78 | CNR1 (0.55) | MAPTLMNAPOLBALDH1A1TSHR | |
| SCHEMBL15034020 | 0.72 | HPGD (0.44) | MAPTLMNAPOLBSMN1; SMN2TP53 | |
| SCHEMBL15020823 | 0.72 | SMN1; SMN2 (0.44) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL15020102 | 0.72 | SMN1; SMN2 (0.44) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL15019469 | 0.72 | SMN1; SMN2 (0.44) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL15020092 | 0.70 | MEN1 (0.55) | MAPTPOLBALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL15034215 | 0.69 | HPGD (0.43) | LMNAALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL19710644 | 0.69 | ALDH1A1 (0.72) | MAPTLMNAPOLBALDH1A1TSHR | |
| SCHEMBL8230032 | 0.69 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237528-A1 | COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237528-A1 | COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | CFTR, PKD1, PKD2 | MAPT 4644/4885LMNA 4295/4885POLB 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.