Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL8587529 | 0.87 | LMNA (0.60) | LMNAHTTSMN1; SMN2GAATHRB | |
| SCHEMBL1574429 | 0.85 | AKR1C3 (0.58) | LMNAGAAAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11003803 | 0.85 | LMNA (0.46) | LMNAHTTSMN1; SMN2GAAAKR1C3 | |
| SCHEMBL5670246 | 0.82 | LMNA (0.51) | LMNAHTTSMN1; SMN2GAATHRB | |
| SCHEMBL2431337 | 0.82 | LMNA (0.51) | LMNAHTTSMN1; SMN2GAATHRB | |
| SCHEMBL27318062 | 0.82 | LMNA (0.51) | LMNAHTTSMN1; SMN2GAATHRB | |
| SCHEMBL23886634 | 0.82 | CYP2C19 (0.48) | LMNAHTTSMN1; SMN2GAAAKR1C3 | |
| Hydrochloric Acid SCHEMBL27318556 | 0.82 | LMNA (0.56) | LMNAHTTSMN1; SMN2GAATHRB | |
| Hydrochloric Acid SCHEMBL27319426 | 0.82 | LMNA (0.56) | LMNAHTTSMN1; SMN2GAATHRB | |
| SCHEMBL1715 | 0.81 | LMNA (0.59) | LMNAHTTSMN1; SMN2GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087654-B | Preparation method of piperidine-4-butylamine | 苏州昊帆生物股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-113087654-A | Preparation method of piperidine-4-butylamine | 苏州昊帆生物股份有限公司 | 2021-07-09 | — | — | CN | claimed |
| WO-2004089357-A2 | ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2004-10-21 | — | — | WO | claimed |
| CN-109206570-B | Flexible physical split-phase supermolecular dynamic polymer and application thereof | 厦门天策材料科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-113087654-B | Preparation method of piperidine-4-butylamine | 苏州昊帆生物股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113087654-B | Preparation method of piperidine-4-butylamine | 苏州昊帆生物股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-108658853-B | 4-nitrogen heteroaryl alkanol compound and synthesis method thereof | 苏州大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113087654-A | Preparation method of piperidine-4-butylamine | 苏州昊帆生物股份有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-113087654-A | Preparation method of piperidine-4-butylamine | 苏州昊帆生物股份有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-109206570-A | A kind of compliant physical split-phase supermolecule dynamic aggregation object and its application | 翁秋梅 | 2019-01-15 | — | — | CN | disclosed |
| CN-105492575-A | Electronically neutral metal complexes as biological labels | RUBIPY SCIENT INC | 2016-04-13 | — | — | CN | disclosed |
| EP-0626957-A1 | STYRIL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| EP-0626939-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1994020455-A1 | STYRYL DERIVATIVES, THEIR PREPARATION AND USE AS PDE-IV INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |
| WO-1994014800-A1 | STYRIL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |
| WO-1994014742-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CELLTECH LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |
| WO-1994010167-A1 | TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |
| EP-0088128-A4 | ANTIINFLAMMATORY AND ANALGETIC 4-PYRIDYLPYRIDAZIN(2H)-3-ONES. | DIAMOND SHAMROCK CORP (US) | 1984-04-06 | — | — | EP | disclosed |
| EP-0088128-A1 | ANTIINFLAMMATORY AND ANALGETIC 4-PYRIDYLPYRIDAZIN(2H)-3-ONES | DIAMOND SHAMROCK CORPORATION (US) | 1983-09-14 | — | — | EP | disclosed |
| WO-1983000863-A1 | ANTIINFLAMMATORY AND ANALGETIC 4-PYRIDYLPYRIDAZIN(2H)-3-ONES | DIAMOND SHAMROCK CORP (US) | 1983-03-17 | — | — | WO | disclosed |