Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178974 | 0.90 | GPR35 (0.40) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14757447 | 0.84 | GPR35 (0.36) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12264654 | 0.81 | CYP2A6 (0.33) | — | |
| SCHEMBL15715104 | 0.79 | GPR35 (0.34) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL845679 | 0.74 | GPR35 (0.50) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12264643 | 0.73 | GAA (0.38) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2397573 | 0.68 | GSK3B (0.47) | ALDH1A1POLBGLAL3MBTL1 | |
| SCHEMBL12073935 | 0.68 | GPR35 (0.41) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12606487 | 0.67 | GPR35 (0.38) | GPR35HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17112945 | 0.64 | GPR35 (0.41) | GPR35HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110226338-A1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | RAYNERGY TEK INC. (TW) | 2011-09-22 | — | — | US | disclosed |
| US-20110226338-A1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | RAYNERGY TEK INC. (TW) | 2011-09-22 | — | — | US | disclosed |