Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271077 | 0.93 | MEN1 (0.48) | SMN1; SMN2HRH3HRH1TDP1KDM4E | |
| SCHEMBL2406071 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1KDM4EKMT2A | |
| SCHEMBL12319348 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EMEN1KMT2ADRD3 | |
| SCHEMBL12266409 | 0.80 | HRH3 (0.49) | SMN1; SMN2HRH3HRH1KDM4EDRD2 | |
| SCHEMBL13383628 | 0.77 | HRH3 (0.51) | SMN1; SMN2HRH3HRH1KDM4EDRD2 | |
| SCHEMBL82435 | 0.75 | HRH3 (0.73) | HRH3KDM4EMAPK14PSMB1PSMB5 | |
| SCHEMBL12035585 | 0.75 | HRH3 (0.73) | HRH3KDM4EMAPK14PSMB1PSMB5 | |
| SCHEMBL12271044 | 0.74 | CYP1A2 (0.55) | SMN1; SMN2HRH1TDP1KDM4EMEN1 | |
| SCHEMBL12266420 | 0.74 | KDM4E (0.55) | SMN1; SMN2HRH3HRH1KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL6473996 | 0.73 | HRH3 (0.71) | HRH3KDM4EMAPK14PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017809-B2 | Bisboron compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-13 | — | — | US | disclosed |