Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD5 | P21918 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.43 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266420 | 0.88 | KDM4E (0.55) | HRH3LTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13383628 | 0.86 | HRH3 (0.51) | HRH3LTA4HKDM4ESMN1; SMN2HRH1 | |
| SCHEMBL12271044 | 0.81 | CYP1A2 (0.55) | LTA4HKDM4EALDH1A1SMN1; SMN2HRH1 | |
| SCHEMBL12266379 | 0.80 | SMN1; SMN2 (0.50) | HRH3KDM4ESMN1; SMN2HRH1DRD3 | |
| SCHEMBL13383619 | 0.78 | HRH1 (0.45) | HRH3LTA4HHRH1DRD1DRD4 | |
| SCHEMBL12270682 | 0.75 | HPGD (0.73) | LTA4HKDM4EALDH1A1SMN1; SMN2LYPLA1 | |
| SCHEMBL12271077 | 0.74 | MEN1 (0.48) | HRH3KDM4EALDH1A1SMN1; SMN2HRH1 | |
| SCHEMBL12270830 | 0.73 | LYPLA1 (0.76) | HRH3LTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12271034 | 0.73 | LYPLA1 (0.48) | KDM4EALDH1A1HRH1LYPLA1LYPLA2 | |
| SCHEMBL8122915 | 0.72 | HRH3 (0.80) | HRH3LTA4HKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8017809-B2 | Bisboron compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | HRH3 2376/4885LTA4H 4297/4885KDM4E 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.