SCHEMBL1228271

SCHEMBL1228271

C=CCCC[Si](C)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718942 0.93 TSHR (0.41) TSHRALDH1A1LMNA
SCHEMBL959298 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL1228272 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL6037408 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL6037441 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL1230177 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL8510858 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL6037409 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL964644 0.91 TSHR (0.44) TSHRALDH1A1LMNA
SCHEMBL6037312 0.91 TSHR (0.44) TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640449-B Preparation method of organic silicon elastomer 江苏德热纳装备科技有限公司 2024-03-26 CN claimed
CN-116640449-A Preparation method of organic silicon elastomer 江苏德热纳装备科技有限公司 2023-08-25 CN claimed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
CN-116640449-B Preparation method of organic silicon elastomer 江苏德热纳装备科技有限公司 2024-03-26 CN disclosed
CN-116640449-A Preparation method of organic silicon elastomer 江苏德热纳装备科技有限公司 2023-08-25 CN disclosed
EP-2462174-A1 BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS Wacker Chemie AG (DE) 2012-06-13 EP disclosed
US-20120136082-A1 BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS WACKER CHEMIE AG (DE) 2012-05-31 US disclosed
US-7994250-B2 Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof KONISHI CO., LTD. (JP) 2011-08-09 US disclosed
WO-2011015547-A1 BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS WACKER CHEMIE AG (DE) 2011-02-10 WO disclosed
US-20090326151-A1 HAIR COSMETIC KONISHI CO., LTD. (JP) 2009-12-31 US disclosed
EP-2039347-A1 COSMETIC HAIR PREPARATION Shiseido Company, Limited (JP) 2009-03-25 EP disclosed
EP-1837360-A1 VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME Konishi Co., Ltd. (JP) 2007-09-26 EP disclosed
US-20070117902-A1 Vinyl-urethane copolymers and production methods thereof KONISHI CO., LTD. (JP) 2007-05-24 US disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed