Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 7/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 5/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858964 | 1.00 | ANPEP (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL7440987 | 0.78 | TSHR (0.35) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL1784326 | 0.77 | RNPEP (0.30) | SLC7A5 | |
| Hydrochloric Acid SCHEMBL7441258 | 0.77 | GMNN (0.35) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL10893754 | 0.76 | TSHR (0.45) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL10714554 | 0.73 | ANPEP (0.40) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL30685387 | 0.73 | TRPV1 (0.31) | — | |
| SCHEMBL6242953 | 0.73 | ANPEP (0.40) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL20177448 | 0.73 | ANPEP (0.40) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL10051070 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070458-A | MICRBIAL ENZYME | SANRAKU-OCEAN CO., LTD. (JA) | 1978-01-24 | — | — | US | claimed |
| EP-2459229-A1 | USE OF CONSTRAINED DIPEPTIDE AND TRIPEPTIDE MIMIC OLIGOMERS AS VECTORIZATION AGENTS | Centre National de la Recherche Scientifique (C.N.R.S.) (FR) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012729-A1 | USE OF CONSTRAINED DIPEPTIDE AND TRIPEPTIDE MIMIC OLIGOMERS AS VECTORIZATION AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-02-03 | — | — | WO | disclosed |
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |