Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 8/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 4/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714554 | 1.00 | ANPEP (0.40) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL6242953 | 1.00 | ANPEP (0.40) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL7383005 | 0.76 | TSHR (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL10715352 | 0.76 | TSHR (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL6120976 | 0.75 | — | — | |
| SCHEMBL13858964 | 0.73 | ANPEP (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL1228290 | 0.73 | ANPEP (0.38) | ANPEPDNPEPSLC7A5LAP3ERAP1 | |
| SCHEMBL9824000 | 0.73 | GABRP (0.52) | ANPEPDNPEPSLC7A5LAP3ALDH1A1 | |
| SCHEMBL9823997 | 0.73 | GABRP (0.52) | ANPEPDNPEPSLC7A5LAP3ALDH1A1 | |
| SCHEMBL7285511 | 0.73 | GABRP (0.52) | ANPEPDNPEPSLC7A5LAP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |