Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.71 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234175 | 1.00 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL29395018 | 1.00 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL20717760 | 0.93 | ESR1 (0.62) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL13066154 | 0.93 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL298393 | 0.93 | ESR1 (0.62) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL20717777 | 0.91 | ESR1 (0.62) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL1021957 | 0.91 | ESR1 (0.61) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL20762234 | 0.88 | ESR1 (0.57) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL1229448 | 0.88 | ESR1 (0.71) | ESR1ESR2KLF10CYP2D6ALOX15 | |
| SCHEMBL8062965 | 0.88 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3386 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660560-B1 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-03-23 | — | — | EP | claimed |
| CN-103497334-A | Copolyetherimides | SABIC INNOVATIVE PLASTICS IP | 2014-01-08 | — | — | CN | claimed |
| US-20140004071-A1 | Thermochromic Dental Material | BROWN WILLIAM STEVEN (US) | 2014-01-02 | — | — | US | claimed |
| EP-2649111-A1 | ISOSORBIDE-CONTAINING POLYCARBONATES AND THEIR PREPARATION | SABIC Innovative Plastics IP B.V. (NL) | 2013-10-16 | — | — | EP | claimed |
| EP-1581594-B1 | POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-03-27 | — | — | EP | claimed |
| US-8372943-B2 | Isosorbide—containing polycarbonates and their preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-02-12 | — | — | US | claimed |
| US-8222347-B2 | Polyester-polycarbonate compositions | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-07-17 | — | — | US | claimed |
| US-20120149863-A1 | ISOSORBIDE - CONTAINING POLYCARBONATES AND THEIR PREPARATION | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2012-06-14 | — | — | US | claimed |
| WO-2012078825-A1 | ISOSORBIDE-CONTAINING POLYCARBONATES AND THEIR PREPARATION | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-06-14 | — | — | WO | claimed |
| JP-4768635-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| WO-2002011134-A1 | DATA STORAGE MEDIA CONTAINING CLEAR POLYCARBONATE TERPOLYMER | GENERAL ELECTRIC COMPANY (US) | 2002-02-07 | — | — | WO | claimed |
| WO-2001094469-A1 | DATA STORAGE MEDIA CONTAINING CLEAR POLYCARBONATE BLENDS | GENERAL ELECTRIC COMPANY (US) | 2001-12-13 | — | — | WO | claimed |
| US-6323304-B1 | CONTACTING A DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF CATALYST COMPRISED OF ALKALI OR ALKALINE EARTH METAL-TRANSITION METAL FLUORIDE COMPOUND AND IN PRESENCE OF COCATALYST | GENERAL ELECTRIC COMPANY | 2001-11-27 | — | — | US | claimed |
| US-6323303-B1 | POLYMERIZING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF A RUTHENIUM (II) OR RUTHENIUM (III) COMPOUND OR COMPLEX; OPTIONALLY IN PRESENCE OF A TETRAALKYL AMMONIUM OR TETRAALKYL PHOSPHONIUM SALT | GENERAL ELECTRIC COMPANY | 2001-11-27 | — | — | US | claimed |
| US-6303737-B1 | POLYCONDENSATION CATALYSTS WHICH ARE SALTS OF CERTAIN PHENANTHROLINE COMPOUNDS; EXCELLENT POLYMERIZATION RATES; REDUCING THE LEVEL OF BRANCHING SIDE REACTION, I.E., FORMATION OF FRIES PRODUCT | GENERAL ELECTRIC COMPANY | 2001-10-16 | — | — | US | claimed |
| US-6291631-B1 | CONTACTING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE POLYMERIZATION CATALYST UNDER POLYCARBONATE MELT POLYMERIZATION CONDITIONS | GENERAL ELECTRIC COMPANY | 2001-09-18 | — | — | US | claimed |
| EP-0175905-B1 | POLYCARBONATE AND ITS USE AS OPTICAL DISC SUBSTRATE | MITSUBISHI KASEI CORPORATION (JP) | 1989-05-31 | — | — | EP | claimed |
| US-4775739-A | IMPROVED FLOWABILITY | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-10-04 | — | — | US | claimed |
| US-4680374-A | RADIATION TRANSPARENT | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1987-07-14 | — | — | US | claimed |
| EP-0175905-A2 | Polycarbonate and its use as optical disc substrate | MITSUBISHI KASEI CORPORATION (JP) | 1986-04-02 | — | — | EP | claimed |