Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.62 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234175 | 0.93 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL122862 | 0.93 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL29395018 | 0.93 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL20762234 | 0.92 | ESR1 (0.57) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL1021957 | 0.91 | ESR1 (0.61) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL7804723 | 0.86 | KLF10 (0.59) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL13066154 | 0.86 | ESR1 (0.71) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL20717760 | 0.86 | ESR1 (0.62) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL20717777 | 0.84 | ESR1 (0.62) | ESR1ESR2KLF10CACNA1BRORC | |
| SCHEMBL5026246 | 0.84 | GABRA1 (0.57) | ESR1ESR2KLF10CACNA1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248859-B1 | CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY | 2001-06-19 | — | — | US | claimed |
| EP-2428528-A1 | Electrical fixture made from DMBPC polycarbonate homopolymer and copolymer | SABIC Innovative Plastics IP B.V. (NL) | 2012-03-14 | — | — | EP | disclosed |
| US-6248859-B1 | CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2001002462-A1 | POLYCARBONATES SUITABLE FOR USE IN OPTICAL ARTICLES | GENERAL ELECTRIC COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |