SCHEMBL1228641

SCHEMBL1228641

Ic1ccc(OCC2CO2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.66
ALDH1A1 P00352 4/20 0.61
TP53 P04637 3/20 0.61
TSHR P16473 3/20 0.61
MAPT P10636 2/20 0.61
HPGD P15428 2/20 0.61
HIF1A Q16665 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
PKM P14618 2/20 0.61
CYP1A2 P05177 1/20 0.61
PPARG P37231 1/20 0.61
LMNA P02545 1/20 0.61
GAA P10253 1/20 0.61
CYP3A4 P08684 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
GLA P06280 1/20 0.46
APP P05067 7/20 0.45
FGFR1 P11362 1/20 0.41
SRC P12931 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965385 1.00 TDP1 (0.66) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL7965384 1.00 TDP1 (0.66) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL11745698 0.94 TDP1 (0.59) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL20677146 0.89 TDP1 (0.79) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL21094081 0.89 TDP1 (0.79) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL50264 0.89 TDP1 (0.79) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL16392443 0.84 TDP1 (0.66) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL14088749 0.83 TDP1 (0.70) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL21202704 0.83 TDP1 (0.70) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL2720991 0.83 TDP1 (0.70) TDP1ALDH1A1TP53TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037009-A Solid catalyst component, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-122037005-A Catalytic composition, catalyst for olefin prepolymerization or polymerization, process for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-122037013-A Catalytic component, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-122037006-A Catalyst component for olefin polymerization, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
EP-3191453-B1 PHENYL-(AZA)CYCLOALKYL CARBOXYLIC ACID GPR120 MODULATORS BRISTOL MYERS SQUIBB CO (US) 2019-10-23 EP disclosed
US-9506003-B2 Lubricants for magnetic recording media AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-11-29 US disclosed
EP-2459570-B1 NITROIMIDAZOOXAZINE ANALOGUES AND THEIR USES GLOBAL ALLIANCE FOR TB DRUG DEV (US) 2014-12-24 EP disclosed
US-8293734-B2 Nitroimidazooxazine and nitroimidazooxazole analogues and their uses GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2012-10-23 US disclosed
EP-2459570-A1 NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES Global Alliance For Tb Drug Development (US) 2012-06-06 EP disclosed
WO-2011014776-A1 NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2011-02-03 WO disclosed
US-20110028466-A1 NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2011-02-03 US disclosed
CN-1315830-A Method for treating anxiety disorders LILLY CO ELI (US) 2001-10-03 CN disclosed
US-6242450-B1 SUBSTITUTED PIPERIDINES ELI LILLY AND COMPANY 2001-06-05 US disclosed
WO-2000006082-A2 TREATMENT OF ANXIETY DISORDERS ELI LILLY AND COMPANY (US) 2000-02-10 WO disclosed
WO-2000006166-A1 5-HT1F ANTAGONISTS ELI LILLY AND COMPANY (US) 2000-02-10 WO disclosed
EP-0976746-A1 5-HT1F antagonists ELI LILLY AND COMPANY (US) 2000-02-02 EP disclosed
EP-0976747-A2 Use of 5HT-1F receptor antagonists for treating anxiety disorders ELI LILLY AND COMPANY (US) 2000-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028466-A1 NITROIMIDAZOOXAZINE AND NITROIMIDAZOOXAZOLE ANALOGUES AND THEIR USES NOX5, NQO2, SIRT5 TDP1 1952/4885ALDH1A1 2444/4885TP53 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.