SCHEMBL1228699

SCHEMBL1228699

c1ccc(COc2ccc(OCC3CO3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.73
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 4/20 0.56
HIF1A Q16665 3/20 0.56
TP53 P04637 3/20 0.56
TSHR P16473 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
CYP3A4 P08684 1/20 0.56
LMNA P02545 2/20 0.55
CYP1A2 P05177 2/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
CYP2C19 P33261 1/20 0.55
PTGS2 P35354 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
MAOB P27338 3/20 0.54
MAPT P10636 3/20 0.54
HPGD P15428 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1351514 1.00 TDP1 (0.73) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL3287709 1.00 TDP1 (0.73) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL7693412 0.98 TDP1 (0.71) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL7693411 0.97 TDP1 (0.69) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL10024632 0.92 TDP1 (0.66) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL5634061 0.91 TDP1 (0.63) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL7999229 0.89 ALDH1A1 (0.75) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL1228760 0.89 TDP1 (0.57) TDP1MEN1KMT2AHIF1ASMN1; SMN2
SCHEMBL7838634 0.89 ALDH1A1 (0.75) TDP1MEN1KMT2AALDH1A1HIF1A
SCHEMBL7113340 0.89 ALDH1A1 (0.75) TDP1MEN1KMT2AALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1128952-A None JP disclosed
CN-113138531-B Resin composition, cured film, and black matrix 新应材股份有限公司 2025-03-28 CN disclosed
CN-115304502-B FOXM1 inhibitor and preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-10-18 CN disclosed
US-20240241439-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM AND BLACK MATRIX Advanced Echem Materials Company Limited (TW) 2024-07-18 US disclosed
CN-118276407-A Photosensitive resin composition, cured film, and black matrix 新应材股份有限公司 2024-07-02 CN disclosed
CN-115304502-A FOXM1 inhibitor and preparation method and application thereof 中国医学科学院医药生物技术研究所 2022-11-08 CN disclosed
US-9849134-B2 Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2017-12-26 US disclosed
US-9849134-B2 Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2017-12-26 US disclosed
US-9849134-B2 Method of improving cognition and social behavior in humans having deficits therein due to neurodegenerative disorders and compounds and compositions therefor THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2017-12-26 US disclosed
EP-3122350-A2 METHOD OF IMPROVING COGNITION AND SOCIAL BEHAVIOR IN HUMANS HAVING DEFICITS THEREIN DUE TO NEUROLOGICAL DISORDERS AND COMPOUNDS AND COMPOSITIONS THEREFOR The Board of Trustees of The Leland Stanford Junior University (US) 2017-02-01 EP disclosed
US-4167581-A 1-ARYLOXY-3-(ACYLAMINO)ALKYLAMINO-2-PROPANOL ADRENERGIC BLOCKING, AGENTS AND CARDIAC STIMULANTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-09-11 US disclosed
US-4143140-A CARDIO-SELECTIVE B-ADRENERGIC STIMULANT; 1-HYDROXYPHENOXY-3-UREIDOETHYLAMINO-2-PROPANOL DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-03-06 US disclosed
US-4139623-A HYPOTENSIVE AGENTS C-G CORP. (US) 1979-02-13 US disclosed
US-4131685-A ADRENERGIC BLOCKING AGENT, CARDIAC STIMULANT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-12-26 US disclosed
US-4080471-A ANTIARRYTHMIA AKTIEBOLAGET HASSLE (SW) 1978-03-21 US disclosed
US-4075208-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed
US-4075335-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed
US-4027027-A BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS CIBA-GEIGY CORPORATION (US) 1977-05-31 US disclosed
US-4020071-A B-ADRENOLYTIC, ANTIARRHYTHMIA CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1977-04-26 US disclosed
US-3956335-A HYPERTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed