SCHEMBL122882

SCHEMBL122882

CCC(C)c1cc(O)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.61
TSHR P16473 1/20 0.57
ALOX15 P16050 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
TYR P14679 5/20 0.43
LMNA P02545 2/20 0.43
CYP2C9 P11712 2/20 0.43
NR1I2 O75469 1/20 0.43
MIF P14174 1/20 0.43
HTT P42858 1/20 0.43
NFE2L2 Q16236 1/20 0.43
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28343867 0.98 RORC (0.59) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL28622220 0.87 TSHR (0.52) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL30763515 0.87 TSHR (0.52) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL7950538 0.86 RORC (0.47) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL1104213 0.85 TSHR (0.61) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL29492442 0.85 TSHR (0.61) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL11674667 0.85 RORC (0.46) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL22500129 0.84 RORC (0.54) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL2720122 0.84 RORC (0.54) RORCTSHRALOX15ALDH1A1HSD17B10
SCHEMBL11800922 0.83 RORC (0.44) RORCTSHRALOX15ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2150 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084226-B1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-02-27 EP claimed
US-8114952-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-02-14 US claimed
US-8106126-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-31 US claimed
EP-2288661-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-03-02 EP claimed
EP-2285903-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-02-23 EP claimed
US-7686997-B2 Comprising a combination of 10 to 80 weight percent of a polyester, 5 to 50 weight percent of a polycarbonate, and 10 to 90 weight percent of a polyester-polycarbonate copolymer; transparent polyester-polycarbonate blends with improved weatherability and/or chemical resistance. SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-30 US claimed
US-7655737-B2 Blend of polycarbonate comprising 10-90 mole percent acrylate units and polyester; improved toughness, impact strength; improvements retained after heat aging or at low temperatures, and obtained without having detrimental effect on other desirable properties such as transparency SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-02 US claimed
WO-2009140611-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-19 WO claimed
US-20090286062-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
WO-2009140610-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-19 WO claimed
US-20090286921-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
EP-2084226-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-08-05 EP claimed
EP-2081992-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE Sabic Innovative Plastics IP B.V. (NL) 2009-07-29 EP claimed
WO-2008063722-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO claimed
US-20080119618-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
WO-2008060726-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-22 WO claimed
US-20080119617-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed