SCHEMBL12288486

SCHEMBL12288486

CCCCNCCC1CCCCCC1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
SIGMAR1 Q99720 4/20 0.47
BCHE P06276 4/20 0.47
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TLR7 Q9NYK1 1/20 0.41
MAPT P10636 1/20 0.41
SAT1 P21673 1/20 0.39
EPHX1 P07099 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629782 1.00 CYP1A2 (0.61) CYP1A2SIGMAR1BCHETSHRALDH1A1
Hydrochloric Acid SCHEMBL1677793 0.98 CYP1A2 (0.59) CYP1A2SIGMAR1BCHETSHRALDH1A1
SCHEMBL27384311 0.98 CYP1A2 (0.58) CYP1A2SIGMAR1BCHETSHRALDH1A1
SCHEMBL6625337 0.94 CYP1A2 (0.59) CYP1A2SIGMAR1BCHETSHRALDH1A1
Hydrochloric Acid SCHEMBL1678031 0.92 CYP1A2 (0.57) CYP1A2SIGMAR1BCHETSHRALDH1A1
SCHEMBL9204445 0.92 CYP1A2 (0.57) CYP1A2SIGMAR1TSHRALDH1A1MAPT
SCHEMBL11230516 0.92 CYP1A2 (0.57) CYP1A2SIGMAR1TSHRALDH1A1MAPT
SCHEMBL5511122 0.92 CYP1A2 (0.68) CYP1A2SIGMAR1BCHETSHRALDH1A1
SCHEMBL9209516 0.90 CYP1A2 (0.54) CYP1A2SIGMAR1TSHRALDH1A1MAPT
SCHEMBL7937894 0.90 CYP1A2 (0.65) CYP1A2SIGMAR1BCHETSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011131697-A1 LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE ORYZON GENOMICS S.A. (ES) 2011-10-27 WO disclosed