Acetic Acid

Acetic Acid

SCHEMBL122895

CC(=O)O.Oc1ccc2[nH]ccc2c1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.78
GAA P10253 1/20 0.78
ALOX15 P16050 1/20 0.78
RAD51 Q06609 1/20 0.78
NPSR1 Q6W5P4 1/20 0.78
TYR P14679 1/20 0.55
PTGS2 P35354 1/20 0.49
MAPT P10636 2/20 0.49
RAB9A P51151 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAOA P21397 3/20 0.48
MAOB P27338 2/20 0.48
CTNNB1 P35222 1/20 0.47
WNT3A P56704 1/20 0.47
SMAD3 P84022 1/20 0.47
NPC1 O15118 2/20 0.46
CYP2A6 P11509 2/20 0.46
AHR P35869 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28265079 0.92 USP2 (0.66) USP2GAAALOX15RAD51NPSR1
SCHEMBL29440252 0.88 USP2 (1.00) USP2GAAALOX15RAD51NPSR1
SCHEMBL50566 0.88 USP2 (1.00) USP2GAAALOX15RAD51NPSR1
SCHEMBL4542260 0.88 USP2 (0.70) USP2GAAALOX15RAD51NPSR1
Water SCHEMBL28220544 0.86 USP2 (0.95) USP2GAAALOX15RAD51NPSR1
Bromide SCHEMBL6029763 0.86 USP2 (0.95) USP2GAAALOX15RAD51NPSR1
Hydrochloric Acid SCHEMBL4718421 0.86 USP2 (0.95) USP2GAAALOX15RAD51NPSR1
Acetic Acid SCHEMBL23646038 0.85 TYR (0.78) USP2GAAALOX15RAD51NPSR1
Acetaldehyde SCHEMBL308459 0.85 USP2 (0.78) USP2GAAALOX15RAD51NPSR1
Trifluoroacetic Acid SCHEMBL30029434 0.84 USP2 (0.70) USP2GAAALOX15RAD51NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 764 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719497-A1 METHODS FOR TREATING SSTR POSITIVE CANCER Rayzebio, Inc. (US) 2026-04-08 EP claimed
US-20250228842-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME Crinetics Pharmaceuticals, Inc. 2025-07-17 US claimed
US-20250041363-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF ALCOHOL USE DISORDER AND ALCOHOL-ASSOCIATED LIVER DISEASE UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. 2025-02-06 US claimed
WO-2024249352-A1 METHODS FOR TREATING SSTR POSITIVE CANCER RAYZEBIO, INC. (US) 2024-12-05 WO claimed
EP-4463159-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME Crinetics Pharmaceuticals, Inc. (US) 2024-11-20 EP claimed
CN-112946150-B Method and kit for rapidly detecting homovanillic acid, vanilla mandelic acid, 5-hydroxy indoleacetic acid and creatinine in human urine 深圳华大临床检验中心 2024-06-18 CN claimed
WO-2023137018-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME Crinetics Pharmaceuticals, Inc. (US) 2023-07-20 WO claimed
CN-114828648-A Pet food compositions 希尔氏宠物营养品公司 2022-07-29 CN claimed
WO-2021221591-A1 SYSTEM AND METHOD MEASURING GLUCOSE FROM URINE ERKEN HAYDAR ALI (TR) 2021-11-04 WO claimed
US-20210198612-A1 APPARATUS FOR ENRICHING AND SCREENING TARGET OBJECT SUCH AS CELL, BACTERIA OR BIOMOLECULE FROM SAMPLE SUZHOU BIOFLUX MEDICAL TECHNOLOGY LTD. (CN) 2021-07-01 US claimed
US-20050181065-A1 Pharmaceutical composition inducing cancer cell differentiation and the use for treatment and prevention of cancer thereof BIO GRAND CO., LTD. (TW) 2005-08-18 US claimed
US-20040131595-A1 Treating carcinoid neoplasms with therapeutic viruses WELLSTAT BIOLOGICS CORPORATION 2004-07-08 US claimed
WO-2004043222-A2 TREATING CARCINOID NEOPLASMS WITH THERAPEUTHIC VIRUSES WELLSTAT BIOLOGICS CORPORATION (US) 2004-05-27 WO claimed
EP-0964875-B1 5-HYDROXYTRYPTOPHOL (5-HTOL) DERIVATIVES, ANTIBODIES, IMMUNOASSAYS AND DETECTION OF RECENT ALCOHOL CONSUMPTION ALCO DIA AB (SE) 2004-03-03 EP claimed
EP-1051179-A2 ANTI-ESTROGEN PLUS PROGESTIN CONTAINING ORAL CONTRACEPTIVES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-15 EP claimed
EP-0964875-A1 5-HYDROXYTRYPTOPHOL (5-HTOL) DERIVATIVES, ANTIBODIES, IMMUNOASSAYS AND DETECTION OF RECENT ALCOHOL CONSUMPTION Axis Biochemicals ASA (NO) 1999-12-22 EP claimed
WO-1999024027-A2 ANTI-ESTROGEN PLUS PROGESTIN CONTAINING ORAL CONTRACEPTIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1999-05-20 WO claimed
WO-1998024819-A1 5-HYDROXYTRYPTOPHOL (5-HTOL) DERIVATIVES, ANTIBODIES, IMMUNOASSAYS AND DETECTION OF RECENT ALCOHOL CONSUMPTION AXIS BIOCHEMICALS ASA (NO) 1998-06-11 WO claimed
EP-0006792-B1 IODINATED COMPOUND USABLE AS RADIO-IMMUNOLOGICAL TRACER AND ITS PROCESS OF PREPARATION COMMISSARIAT A L'ENERGIE ATOMIQUE Etablissement de Caractère Scientifique Technique et Industriel (FR) 1982-06-23 EP claimed
US-4331646-A Iodine compound for use as a tracer in radioimmunology COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1982-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228842-A1 USES OF A SOMATOSTATIN MODULATOR FOR THE TREATMENT OF CARCINOID SYNDROME SSTR4, SSTR5, SSTR2 USP2 2056/4885GAA 1778/4885ALOX15 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.