Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR known ✓ | Q92847 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.78 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355861 | 0.88 | TYR (1.00) | TYRENPP2KDM4EALDH1A1HPGD | |
| SCHEMBL34240 | 0.88 | TYR (1.00) | TYRENPP2KDM4EALDH1A1HPGD | |
| Acetic Acid SCHEMBL122895 | 0.85 | USP2 (0.78) | TYRENPP2KDM4EALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL29374819 | 0.83 | TYR (0.81) | TYRENPP2KDM4EALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL23541029 | 0.83 | TYR (0.81) | TYRENPP2KDM4EALDH1A1HPGD | |
| SCHEMBL6717966 | 0.81 | TYR (0.60) | TYRENPP2KDM4EALDH1A1HPGD | |
| SCHEMBL5447196 | 0.81 | TYR (0.84) | TYRENPP2KDM4EALDH1A1HPGD | |
| Acetic Acid SCHEMBL9120361 | 0.80 | AHR (0.75) | TYRENPP2KDM4EALDH1A1HPGD | |
| Acetic Acid SCHEMBL27626529 | 0.80 | AHR (0.75) | TYRENPP2KDM4EALDH1A1HPGD | |
| Acetic Acid SCHEMBL9119235 | 0.80 | AHR (0.75) | TYRENPP2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11331336-B2 | Pet food compositions | HILLS PET NUTRITION, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210220385-A1 | PET FOOD COMPOSITIONS | HILL'S PET NUTRITION, INC. (US) | 2021-07-22 | — | — | US | disclosed |