SCHEMBL12290355

SCHEMBL12290355

Cc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc2c1OCCO2

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAS2R8 Q9NYW2 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1649359 0.91 TAS2R8 (1.00) TAS2R8
SCHEMBL1279043 0.90 TAS2R8 (1.00) TAS2R8
SCHEMBL1651450 0.87 TAS2R8 (1.00) TAS2R8
SCHEMBL1279345 0.82 TAS2R8 (1.00) TAS2R8
SCHEMBL1652683 0.82 TAS2R8 (1.00) TAS2R8
SCHEMBL1279531 0.81 TAS2R8 (1.00) TAS2R8
SCHEMBL1650803 0.81 TAS2R8 (1.00) TAS2R8
SCHEMBL13940499 0.81 TAS2R8 (0.80) TAS2R8
SCHEMBL1650405 0.81 TAS2R8 (1.00) TAS2R8
SCHEMBL1279056 0.79 TAS2R8 (1.00) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011106114-A1 IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE SENOMYX, INC. (US) 2011-09-01 WO disclosed