Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279205 | 0.92 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279209 | 0.92 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279690 | 0.92 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1615866 | 0.83 | TAS2R8 (0.85) | TAS2R8 | |
| SCHEMBL1616744 | 0.83 | TAS2R8 (0.85) | TAS2R8 | |
| SCHEMBL13940245 | 0.83 | TAS2R8 (0.69) | TAS2R8 | |
| SCHEMBL12290402 | 0.83 | TAS2R8 (0.84) | TAS2R8 | |
| SCHEMBL1279395 | 0.81 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279186 | 0.81 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279181 | 0.81 | TAS2R8 (1.00) | TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106114-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE | SENOMYX, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2009025793-A2 | HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF | SENOMYX, INC. (US) | 2009-02-26 | — | — | WO | disclosed |