Tryptophan Methyl Ester

Tryptophan Methyl Ester

SCHEMBL122907

COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
KDM4E B2RXH2 2/20 0.70
MAPT P10636 2/20 0.70
LMNA P02545 1/20 0.70
MPO P05164 1/20 0.70
TSHR P16473 1/20 0.70
BLM P54132 1/20 0.70
PMP22 Q01453 1/20 0.70
HIF1A Q16665 1/20 0.70
TACR1 P25103 2/20 0.67
HTR2A P28223 2/20 0.60
ADRB1 P08588 1/20 0.60
HTR1A P08908 1/20 0.60
ADRA2A P08913 1/20 0.60
SLC6A2 P23975 1/20 0.60
HTR1D P28221 1/20 0.60
HTR1B P28222 1/20 0.60
HTR2C P28335 1/20 0.60
HTR1E P28566 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan Methyl Ester SCHEMBL1195735 1.00 MEN1 (0.70) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL30180690 1.00 MEN1 (0.70) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL475267 1.00 MEN1 (0.70) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL19161138 1.00 MEN1 (0.70) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL475266 0.99 MEN1 (0.68) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL29401004 0.99 MEN1 (0.68) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL29398306 0.99 MEN1 (0.68) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL378072 0.99 MEN1 (0.68) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL378071 0.99 MEN1 (0.68) MEN1KMT2AKDM4EMAPTLMNA
Tryptophan Methyl Ester SCHEMBL28130766 0.99 KDM4E (0.72) MEN1KMT2AKDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2897 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119679051-B Method for preparing premixed feed from tryptophan fermentation broth 山东天力药业有限公司 2025-05-27 CN claimed
CN-119874660-A Amino acid derivative-rhodamine B conjugate, preparation method thereof and application thereof as fluorescent tracer 内蒙古农业大学 2025-04-25 CN claimed
CN-119776848-A Green corrosion inhibitor and preparation method and application thereof 三峡金沙江云川水电开发有限公司 2025-04-08 CN claimed
CN-119679051-A Method for preparing premixed feed from tryptophan fermentation broth 山东天力药业有限公司 2025-03-25 CN claimed
CN-119661396-A Preparation method of gamma-amino acid derivative or dipeptide 中国科学院大连化学物理研究所 2025-03-21 CN claimed
CN-118994439-B Preparation and application of hyaluronic acid-based composite polymer material 杭州皓阳生物技术有限公司 2025-02-18 CN claimed
CN-119470406-A Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof 山东新华莎罗雅生物技术有限公司 2025-02-18 CN claimed
CN-119409588-A Caffeoyl amino acid methyl ester derivative and preparation method and application thereof 西北大学 2025-02-11 CN claimed
CN-119409587-A Amino acid derivative of 2,2 '-binaphthyl-6, 6' -dicarboxylic acid, and preparation method and application thereof 武汉大学人民医院(湖北省人民医院) 2025-02-11 CN claimed
CN-119409631-A 2,2 '-Biquinoline-4, 4' -dicarboxylic acid amino acid derivative, and preparation method and application thereof 武汉大学人民医院(湖北省人民医院) 2025-02-11 CN claimed
EP-1127875-A1 Process for the preparation of alpha-dimethylaminomethyl-tryptophan methyl ester WARNER-LAMBERT COMPANY (US) 2001-08-29 EP claimed
WO-2001060986-A2 ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY THERMOGEN, INC. (US) 2001-08-23 WO claimed
WO-2001046176-A2 NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 2001-06-28 WO claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
US-5736518-A Peptide compounds of (L) amino acids and ring molecules, and therapeutical applications thereof POLIFARMA S.P.A. (IT) 1998-04-07 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
US-5504071-A HYPOTENSIVE AGENTS POLIFARMA S.P.A. (IT) 1996-04-02 US claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
US-4622420-A Chelating agents and method THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1986-11-11 US claimed