Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15990743 | 0.84 | USP2 (0.47) | MAOBUSP2L3MBTL1CA9CA12 | |
| SCHEMBL20788133 | 0.83 | USP2 (0.48) | USP2L3MBTL1CA9CA12ESR1 | |
| SCHEMBL1104936 | 0.83 | USP2 (0.53) | MAOBUSP2L3MBTL1CA9CA12 | |
| SCHEMBL1104941 | 0.82 | USP2 (0.49) | MAOBUSP2L3MBTL1MEN1KMT2A | |
| SCHEMBL30125078 | 0.82 | USP2 (0.49) | MAOBUSP2L3MBTL1MEN1KMT2A | |
| SCHEMBL14527749 | 0.82 | USP2 (0.55) | USP2L3MBTL1CA9CA12ESR1 | |
| SCHEMBL10268461 | 0.82 | USP2 (0.55) | USP2L3MBTL1MAPTCA9CA12 | |
| SCHEMBL31621793 | 0.82 | USP2 (0.55) | USP2L3MBTL1MAPTCA9CA12 | |
| SCHEMBL10205413 | 0.80 | PTPN11 (0.54) | USP2L3MBTL1CA9CA12ESR1 | |
| SCHEMBL15298865 | 0.80 | USP2 (0.56) | USP2L3MBTL1MAPTCA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8021647-B2 | In vivo optical imaging | GENERAL ELECTRIC COMPANY (US) | 2011-09-20 | — | — | US | disclosed |
| US-8021647-B2 | In vivo optical imaging | GENERAL ELECTRIC COMPANY (US) | 2011-09-20 | — | — | US | disclosed |
| US-20090004116-A1 | IN VIVO OPTICAL IMAGING | GENERAL ELECTRIC COMPANY (US) | 2009-01-01 | — | — | US | disclosed |
| US-20090004116-A1 | IN VIVO OPTICAL IMAGING | GENERAL ELECTRIC COMPANY (US) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090004116-A1 | IN VIVO OPTICAL IMAGING | ALDH1A2, GUSB, ENGASE | MAOB 168/4885USP2 1600/4885L3MBTL1 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.