SCHEMBL12291373

SCHEMBL12291373

CCCC(=O)CCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.62
EPHX2 P34913 1/20 0.48
CASP3 P42574 1/20 0.43
TLR2 O60603 2/20 0.42
FABP5 Q01469 2/20 0.41
FABP7 O15540 1/20 0.41
CXCR2 P25025 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13124061 0.90 KMT2A (0.67) KMT2AEPHX2TLR2
SCHEMBL92796 0.88 KMT2A (0.66) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL31419531 0.88 KMT2A (0.66) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL18290276 0.87 KMT2A (0.65) KMT2AEPHX2CASP3FABP5FABP7
Hydrochloric Acid SCHEMBL31419532 0.87 KMT2A (0.64) KMT2AEPHX2CASP3TLR2FABP5
SCHEMBL3515002 0.86 KMT2A (0.68) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL4557899 0.86 KMT2A (0.68) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL28429395 0.86 KMT2A (0.71) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL31270657 0.86 KMT2A (0.71) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL12665707 0.85 KMT2A (0.67) KMT2AEPHX2CASP3FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2368908-A2 Anti- angiogenic compounds CovX Technologies Ireland Limited (IE) 2011-09-28 EP disclosed
EP-2292248-A2 Anti-angiogenic compounds CovX Technologies Ireland Limited (IE) 2011-03-09 EP disclosed