Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19240089 | 0.88 | ALDH1A1 (0.48) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL14456204 | 0.86 | ALDH1A1 (0.49) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL20805921 | 0.85 | TSHR (0.45) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL13609918 | 0.83 | ALDH1A1 (0.56) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL12260843 | 0.81 | MAPT (0.42) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL12292355 | 0.81 | MAPT (0.42) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL9889261 | 0.81 | MAPT (0.42) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL19240031 | 0.76 | ALDH1A1 (0.64) | TSHRNPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL12292490 | 0.76 | TSHR (0.46) | TSHRNPSR1MAPTNAAAALDH1A1 | |
| SCHEMBL12292489 | 0.76 | TSHR (0.46) | TSHRNPSR1MAPTNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113719-A2 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2011-09-22 | — | — | WO | disclosed |