SCHEMBL12292595

SCHEMBL12292595

N[C@](CCCCB(O)O)(C(=O)O)C1CCN(Cc2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 20/20 1.00
ARG2 P78540 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL895258 1.00 ARG1 (1.00) ARG1ARG2
SCHEMBL895255 1.00 ARG1 (1.00) ARG1ARG2
Hydrochloric Acid SCHEMBL895558 0.99 ARG1 (0.98) ARG1ARG2
SCHEMBL894219 0.93 ARG1 (0.88) ARG1ARG2
SCHEMBL894218 0.93 ARG1 (0.88) ARG1ARG2
SCHEMBL895519 0.93 ARG1 (0.88) ARG1ARG2
Hydrochloric Acid SCHEMBL894985 0.92 ARG1 (0.86) ARG1ARG2
Hydrochloric Acid SCHEMBL895127 0.92 ARG1 (0.86) ARG1ARG2
Hydrochloric Acid SCHEMBL894986 0.92 ARG1 (0.86) ARG1ARG2
SCHEMBL894945 0.91 ARG1 (1.00) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011133653-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS MARS, INCORPORATED (US) 2011-10-27 WO disclosed