Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793548 | 0.87 | MEN1 (0.81) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL13452272 | 0.87 | MAPT (0.65) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL14546814 | 0.85 | MAPT (0.66) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL6995384 | 0.85 | PIK3CD (0.65) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL12292669 | 0.82 | MEN1 (0.52) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL15721518 | 0.81 | MEN1 (0.64) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL190100 | 0.80 | MEN1 (0.80) | MAPTMEN1KMT2APIK3CGPIK3CD | |
| SCHEMBL188640 | 0.80 | PIK3CD (0.69) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL1791272 | 0.80 | MEN1 (0.76) | MAPTMEN1KMT2AL3MBTL1PIK3CG | |
| SCHEMBL15256361 | 0.79 | MEN1 (0.64) | MAPTMEN1KMT2AL3MBTL1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364974-A1 | N-(3-Phenylamino-quinoxalin-2-yl)-benzenesulfonamide derivatives as phosphatidylinositol 3-kinase inhibitors | Exelixis, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2007044729-A2 | N- (3-AMINO-QUINOXALIN-2-YL) -SULFONAMIDE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | EXELIXIS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |