2-Chlorophenol

2-Chlorophenol

SCHEMBL1229280

[Al+3].[O-]c1ccccc1Cl.[O-]c1ccccc1Cl.[O-]c1ccccc1Cl

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
LMNA P02545 1/20 0.62
ALDH1A1 P00352 3/20 0.41
CYP2A6 P11509 4/20 0.38
CYP1A2 P05177 3/20 0.38
IDO1 P14902 2/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
PNMT P11086 1/20 0.36
TAAR1 Q96RJ0 1/20 0.33
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Chlorophenol SCHEMBL31616214 0.94
2-Chlorophenol SCHEMBL6065580 0.94
2-Chlorophenol SCHEMBL29130613 0.94 TSHR (0.62) TSHRLMNAALDH1A1CYP2A6CYP1A2
2-Chlorophenol SCHEMBL1230203 0.94 TSHR (0.62) TSHRLMNAALDH1A1CYP2A6CYP1A2
2-Chlorophenol SCHEMBL3225047 0.94
2-Chlorophenol SCHEMBL6763626 0.94
2-Chlorophenol SCHEMBL1230537 0.94 TSHR (0.62) TSHRLMNAALDH1A1CYP2A6CYP1A2
2-Chlorophenol SCHEMBL11881746 0.91 TSHR (0.59) TSHRLMNAALDH1A1CYP2A6CYP1A2
1,2-Dichlorobenzene SCHEMBL1155123 0.79 TSHR (1.00) TSHRLMNAALDH1A1CYP2A6CYP1A2
1,2-Dichlorobenzene SCHEMBL5190 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746134-B1 CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS KANEKA CORP (JP) 2019-09-04 EP disclosed
EP-1746135-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2019-05-29 EP disclosed
US-7973108-B2 Curable composition KANEKA CORPORATION (JP) 2011-07-05 US disclosed
WO-2011072056-A2 CURE RATE CONTROL FOR ALKOXYSILYL-END-BLOCKED POLYMERS DOW CORNING COPORATION (US) 2011-06-16 WO disclosed
US-7910681-B2 Curable composition having improved adhesion KANEKA CORPORATION (JP) 2011-03-22 US disclosed
US-7893170-B2 Curable composition having improved curability and adhesion KANEKA CORPORATION (JP) 2011-02-22 US disclosed
US-20080319152-A1 Curable Composition KANEKA CORPORATION (JP) 2008-12-25 US disclosed
US-20080194773-A1 Polysiloxane from silanetriol group, a titanium, aluminum or a zirconium catalyst, and a low molecular weight compound containing a hydrolyzable silicon group; sealants, adhesives KANEKA CORPORATION (JP) 2008-08-14 US disclosed
US-20080076878-A1 Organic polymer having a silane tiol group, a titanium, aluminum or a zirconium catalyst, and a low molecular weight compound containing a hydrolyzable silicon group; sealants, adhesives KANEKA CORPORATION (JP) 2008-03-27 US disclosed
EP-1746133-A1 CURABLE COMPOSITION IMPROVED IN ADHESIVENESS Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1746135-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2007-01-24 EP disclosed
EP-1746134-A1 CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS Kaneka Corporation (JP) 2007-01-24 EP disclosed