⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13260290 | 0.91 | MEN1 (0.37) | — | |
| SCHEMBL24268905 | 0.85 | — | — | |
| SCHEMBL853114 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL22990165 | 0.82 | MEN1 (0.36) | — | |
| SCHEMBL29347386 | 0.82 | MEN1 (0.41) | — | |
| SCHEMBL21049142 | 0.81 | — | — | |
| SCHEMBL15844730 | 0.80 | — | — | |
| SCHEMBL20412499 | 0.78 | EPAS1 (0.33) | — | |
| SCHEMBL3482710 | 0.77 | — | — | |
| SCHEMBL9746214 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023088441-A1 | KIF18A INHIBITOR | 微境生物医药科技(上海)有限公司 | 2023-05-25 | — | — | WO | disclosed |
| WO-2011132764-A1 | PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM | FUJIFILM CORPORATION (JP) | 2011-10-27 | — | — | WO | disclosed |