Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTSA | P10619 | 4/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.46 |
| ▸ | GSK3A | P49840 | 4/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | CDK3 | Q00526 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401117 | 1.00 | POLB (0.51) | POLBCTSATNIKABL1RIOK2 | |
| SCHEMBL12268840 | 0.84 | CTSA (0.46) | CTSATNIKABL1RIOK2CDK9 | |
| SCHEMBL2401116 | 0.84 | CTSA (0.46) | CTSATNIKABL1RIOK2CDK9 | |
| SCHEMBL2401409 | 0.84 | CTSA (0.46) | CTSATNIKABL1RIOK2CDK9 | |
| SCHEMBL12661743 | 0.84 | CDK9 (0.58) | POLBCDK9GSK3ACDK1CCNT1 | |
| SCHEMBL1849202 | 0.84 | CDK9 (0.58) | POLBCDK9GSK3ACDK1CCNT1 | |
| SCHEMBL1853448 | 0.84 | CDK9 (0.58) | POLBCDK9GSK3ACDK1CCNT1 | |
| SCHEMBL2382068 | 0.84 | GSK3A (0.55) | CTSARIOK2PSEN1PSEN2APH1B | |
| SCHEMBL27901089 | 0.83 | POLB (0.53) | POLBRIOK2PSEN1PSEN2APH1B | |
| SCHEMBL27901120 | 0.83 | POLB (0.53) | POLBRIOK2PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110612-A1 | INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2011-09-15 | — | — | WO | disclosed |