Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295191 | 0.81 | PIM1 (0.41) | JAK2TYK2HRH4CYP2C19LRRK2 | |
| SCHEMBL10223327 | 0.79 | CYP2C19 (0.58) | CYP2C19LRRK2PIK3CAKMO | |
| SCHEMBL25142286 | 0.78 | JAK2 (0.47) | JAK2TYK2HRH4CYP2C19LRRK2 | |
| SCHEMBL20241721 | 0.78 | PIK3CA (0.42) | JAK2TYK2HRH4CYP2C19LRRK2 | |
| SCHEMBL14872324 | 0.78 | HRH4 (0.50) | JAK2TYK2HRH4CYP2C19LRRK2 | |
| SCHEMBL14868457 | 0.78 | HRH4 (0.43) | JAK2TYK2HRH4CYP2C19LRRK2 | |
| SCHEMBL11960308 | 0.77 | HRH4 (0.53) | HRH4CYP2C19 | |
| SCHEMBL11960323 | 0.77 | SMN1; SMN2 (0.46) | HRH4CYP2C19LRRK2 | |
| SCHEMBL19703400 | 0.77 | PIK3CD (0.42) | JAK2TYK2TLR9TLR8TLR7 | |
| SCHEMBL10255064 | 0.76 | TLR9 (0.37) | TLR9TLR8TLR7OGAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113802-A2 | IMIDAZOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2011-09-22 | — | — | WO | disclosed |