Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14240724 | 1.00 | PLA2G2C (0.44) | PLA2G2CPLA2G10ADRA1ANOD1TSHR | |
| SCHEMBL12664911 | 0.90 | PLA2G2C (0.49) | PLA2G2CPLA2G10NOD1TSHRFAAH | |
| SCHEMBL27329731 | 0.88 | FAAH (0.53) | PLA2G2CPLA2G10NOD1FAAHMEN1 | |
| SCHEMBL25666774 | 0.86 | PLA2G2C (0.53) | PLA2G2CPLA2G10NOD1TSHRFAAH | |
| SCHEMBL24486692 | 0.85 | PLA2G2C (0.42) | PLA2G2CPLA2G10TSHRLMNANFKB1 | |
| SCHEMBL173035 | 0.85 | PLA2G2C (0.42) | PLA2G2CPLA2G10TSHRLMNANFKB1 | |
| SCHEMBL23447066 | 0.85 | PAOX (0.38) | PLA2G2CPLA2G10NOD1FAAHMEN1 | |
| SCHEMBL29880335 | 0.84 | PLA2G2C (0.63) | PLA2G2CPLA2G10NOD1TSHRFAAH | |
| SCHEMBL21686230 | 0.84 | PLA2G2C (0.63) | PLA2G2CPLA2G10NOD1TSHRFAAH | |
| SCHEMBL9127074 | 0.84 | PLA2G2C (0.63) | PLA2G2CPLA2G10NOD1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117416-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2011-09-29 | — | — | WO | disclosed |