Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11978271 | 0.77 | CFTR (0.44) | CFTRIKBKB | |
| SCHEMBL30259615 | 0.77 | CFTR (0.44) | CFTRIKBKB | |
| SCHEMBL12295840 | 0.76 | CFTR (0.87) | CFTR | |
| SCHEMBL18293452 | 0.75 | CFTR (0.42) | CFTRIKBKB | |
| SCHEMBL2372904 | 0.74 | CFTR (0.68) | CFTR | |
| SCHEMBL18289573 | 0.73 | CFTR (0.47) | CFTRIKBKB | |
| SCHEMBL2373012 | 0.73 | CFTR (0.70) | CFTR | |
| SCHEMBL29699252 | 0.73 | CFTR (0.70) | CFTR | |
| SCHEMBL14789606 | 0.71 | CFTR (0.60) | CFTR | |
| SCHEMBL14783594 | 0.71 | CFTR (0.76) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113894-A1 | PYRIDINE AND PYRAZINE DERIVATIVE FOR THE TREATMENT OF CF | NOVARTIS AG (CH) | 2011-09-22 | — | — | WO | disclosed |