Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294854 | 0.80 | SMN1; SMN2 (0.62) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL14760978 | 0.77 | CYP2C9 (0.53) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL12294560 | 0.74 | MAPK1 (0.54) | KMT2AALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL2265406 | 0.72 | MAPK1 (0.51) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL2420499 | 0.71 | CYP2C9 (0.63) | KDM4EL3MBTL1SMN1; SMN2LMNAPKM | |
| SCHEMBL12294634 | 0.71 | CYP2C9 (0.41) | MEN1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL18629838 | 0.70 | SMN1; SMN2 (0.52) | ALDH1A1MAPK1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL12295364 | 0.70 | MAPK1 (0.75) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL12295260 | 0.69 | CYP2C9 (0.58) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL17876756 | 0.69 | KDM4E (0.67) | MEN1KMT2AALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113606-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2011-09-22 | — | — | WO | disclosed |