Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447543 | 0.89 | CYP2C9 (0.59) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL17876755 | 0.86 | CYP2C9 (0.62) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL17876455 | 0.86 | SMN1; SMN2 (0.66) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL17876754 | 0.85 | CYP2C9 (0.62) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL12294854 | 0.84 | SMN1; SMN2 (0.62) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL12294561 | 0.82 | KDM4E (0.58) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL12294409 | 0.82 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL12295260 | 0.82 | CYP2C9 (0.58) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL12294652 | 0.82 | CYP2C9 (0.66) | KDM4ESMN1; SMN2LMNAHTTPKM | |
| SCHEMBL12294653 | 0.81 | KDM4E (0.58) | KDM4ESMN1; SMN2LMNAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185774-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185774-A1 | Anti-Infective Compounds | RABGGTB, ELANE, SERPINB1 | KDM4E 4439/4885SMN1; SMN2 4839/4885LMNA 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.