SCHEMBL12299282

SCHEMBL12299282

CC/C(C)=N/C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1933565 1.00
SCHEMBL9969955 1.00
Trifluoroacetic Acid SCHEMBL22737 0.77 FFAR3 (0.33)
SCHEMBL1253526 0.72 ALDH1A1 (0.38)
SCHEMBL12582321 0.72
SCHEMBL5376437 0.72
SCHEMBL5376439 0.72
SCHEMBL30285875 0.72 ALDH1A1 (0.38)
SCHEMBL12316258 0.72
SCHEMBL10757825 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180153958-A1 CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES CYPRALIS LIMITED (GB) 2018-06-07 US disclosed
US-9895412-B2 Cyclic depsipeptide compounds and their uses CYPRALIS LIMITED (GB) 2018-02-20 US disclosed
US-20170349675-A1 NEW POLYOLEFIN CATALYST AND USE THEREOF SHANGHAI CHEMRUN CO. LTD. (CN) 2017-12-07 US disclosed
US-9629924-B2 Conjugates of CC-1065 analogs and bifunctional linkers SYNTARGA BV (NL) 2017-04-25 US disclosed
US-20170007664-A1 CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES CYPRALIS LIMITED (GB) 2017-01-12 US disclosed
US-20160301014-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-10-13 US disclosed
US-9382295-B2 Cyclic depsipeptide compounds and their uses CYPRALIS LIMITED (GB) 2016-07-05 US disclosed
US-20160058882-A1 CYTOTOXIC AGENTS COMPRISING NEW ANSAMITOCIN DERIVATIVES IMMUNOGEN, INC. 2016-03-03 US disclosed
US-20150313959-A1 NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE PERIOC LTD (GB) 2015-11-05 US disclosed
US-20150259386-A1 CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES CYPRALIS LIMITED (GB) 2015-09-17 US disclosed
EP-2530758-A1 LUMINESCENT COMPOSITION AND LIGHT-EMITTING ELEMENT USING SAID COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2012-12-05 EP disclosed
US-8324204-B2 Fused thiophene derivatives as kinase inhibitors UCB PHARMA SA (BE) 2012-12-04 US disclosed
US-20110218188-A1 SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2011-09-08 US disclosed
US-20110196147-A1 INHIBITORS OF HISTONE DEACETYLASE FMR LLC 2011-08-11 US disclosed
EP-2289966-A1 COPOLYMER AND POLYMER LIGHT-EMITTING ELEMENT USING THE SAME Sumitomo Chemical Company, Limited (JP) 2011-03-02 EP disclosed
US-20100305066-A1 Fused Thiophene Derivatives as Kinase Inhibitors UCB PHARMA S.A. (BE) 2010-12-02 US disclosed
US-20100022509-A1 Inhibitors of MshC and Homologs Thereof, and Methods of Identifying Same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-28 US disclosed
US-20100022509-A1 Inhibitors of MshC and Homologs Thereof, and Methods of Identifying Same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-28 US disclosed
US-20090264411-A1 FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS UCB PHARMA S.A. (BE) 2009-10-22 US disclosed
WO-2008036139-A2 INHIBITORS OF MSHC AND HOMOLOGS THEREOF, AND METHODS OF IDENTIFYING SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-27 WO disclosed