Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30506419 | 0.85 | CYP3A4 (0.67) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL21275479 | 0.85 | CYP3A4 (0.67) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL2874467 | 0.85 | CYP3A4 (0.67) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL30002388 | 0.85 | CYP3A4 (0.67) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL11105157 | 0.83 | CYP3A4 (0.65) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL7901522 | 0.83 | CYP3A4 (0.65) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL7192880 | 0.82 | CYP3A4 (0.63) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL28047701 | 0.81 | CYP3A4 (0.61) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL28370780 | 0.80 | CYP3A4 (0.76) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL25304726 | 0.80 | CYP3A4 (0.59) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230486-A1 | Modulators Of HEC1 Activity And Methods Therefor | TAIVEX THERAPEUTICS CORPORATION (TW) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230486-A1 | Modulators Of HEC1 Activity And Methods Therefor | WEE1, WEE2, NEK11 | CYP3A4 3834/4885USP2 1309/4885MAPK1 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.