Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 6/20 | 0.35 |
| ▸ | CES2 | O00748 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1228632 | 1.00 | TSHR (0.43) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL16105719 | 0.96 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL29564735 | 0.96 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL39696 | 0.96 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1228584 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1228550 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1230019 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL8195406 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1182630 | 0.92 | — | — | |
| SCHEMBL1229359 | 0.92 | TSHR (0.43) | TSHRLMNATHRBCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746134-B1 | CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS | KANEKA CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| EP-1746135-B1 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2019-05-29 | — | — | EP | disclosed |
| US-7973108-B2 | Curable composition | KANEKA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| WO-2011072056-A2 | CURE RATE CONTROL FOR ALKOXYSILYL-END-BLOCKED POLYMERS | DOW CORNING COPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| US-7910681-B2 | Curable composition having improved adhesion | KANEKA CORPORATION (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7893170-B2 | Curable composition having improved curability and adhesion | KANEKA CORPORATION (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20080319152-A1 | Curable Composition | KANEKA CORPORATION (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080194773-A1 | Polysiloxane from silanetriol group, a titanium, aluminum or a zirconium catalyst, and a low molecular weight compound containing a hydrolyzable silicon group; sealants, adhesives | KANEKA CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080076878-A1 | Organic polymer having a silane tiol group, a titanium, aluminum or a zirconium catalyst, and a low molecular weight compound containing a hydrolyzable silicon group; sealants, adhesives | KANEKA CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1746134-A1 | CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS | Kaneka Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1746133-A1 | CURABLE COMPOSITION IMPROVED IN ADHESIVENESS | Kaneka Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1746135-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |